{"id":1919,"date":"2024-02-06T15:04:04","date_gmt":"2024-02-06T14:04:04","guid":{"rendered":"https:\/\/www.chu-tours.fr\/pemr-cvl\/?page_id=1919"},"modified":"2024-02-06T16:04:41","modified_gmt":"2024-02-06T15:04:41","slug":"centre-de-reference-constitutif-maladies-pulmonaires-rares-region-centre-val-de-loire","status":"publish","type":"page","link":"https:\/\/www.chu-tours.fr\/pemr-cvl\/centre-de-reference-constitutif-maladies-pulmonaires-rares-region-centre-val-de-loire\/","title":{"rendered":"Centre de R\u00e9f\u00e9rence Constitutif Maladies Pulmonaires Rares  R\u00e9gion Centre-Val de Loire"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"1919\" class=\"elementor elementor-1919\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-7a00a104 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"7a00a104\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-6fe6aa7f\" data-id=\"6fe6aa7f\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-650e127a elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"650e127a\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-inner-column elementor-element elementor-element-301516e0\" data-id=\"301516e0\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-c8f3b60 elementor-widget elementor-widget-image\" data-id=\"c8f3b60\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.23.0 - 15-07-2024 *\/\n.elementor-widget-image{text-align:center}.elementor-widget-image a{display:inline-block}.elementor-widget-image a img[src$=\".svg\"]{width:48px}.elementor-widget-image img{vertical-align:middle;display:inline-block}<\/style>\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"820\" height=\"321\" src=\"https:\/\/www.chu-tours.fr\/pemr-cvl\/wp-content\/uploads\/sites\/15\/2024\/02\/logo_CRMPR.jpg\" class=\"attachment-large size-large wp-image-1916\" alt=\"Centre de R\u00e9f\u00e9rence Constitutif Maladies Pulmonaires Rares R\u00e9gion Centre-Val de Loire\" srcset=\"https:\/\/www.chu-tours.fr\/pemr-cvl\/wp-content\/uploads\/sites\/15\/2024\/02\/logo_CRMPR.jpg 820w, https:\/\/www.chu-tours.fr\/pemr-cvl\/wp-content\/uploads\/sites\/15\/2024\/02\/logo_CRMPR-300x117.jpg 300w, https:\/\/www.chu-tours.fr\/pemr-cvl\/wp-content\/uploads\/sites\/15\/2024\/02\/logo_CRMPR-768x301.jpg 768w\" sizes=\"(max-width: 820px) 100vw, 820px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-inner-column elementor-element elementor-element-250c7a9d\" data-id=\"250c7a9d\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-58691aa elementor-widget elementor-widget-text-editor\" data-id=\"58691aa\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.23.0 - 15-07-2024 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#69727d;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#69727d;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t<h3 style=\"text-align: center;\">Centre de R\u00e9f\u00e9rence Constitutif Maladies Pulmonaires Rares<br \/>R\u00e9gion Centre-Val de Loire<\/h3>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-inner-column elementor-element elementor-element-5056ca1e\" data-id=\"5056ca1e\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-8d02f3a elementor-widget elementor-widget-image\" data-id=\"8d02f3a\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"207\" height=\"83\" src=\"https:\/\/www.chu-tours.fr\/pemr-cvl\/wp-content\/uploads\/sites\/15\/2024\/02\/logo_Respifil.png\" class=\"attachment-large size-large wp-image-1917\" alt=\"RESPIFIL\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-7b291145 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"7b291145\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-16c3e1ea\" data-id=\"16c3e1ea\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-191d2246 elementor-widget elementor-widget-text-editor\" data-id=\"191d2246\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><strong>Le Centre de r\u00e9f\u00e9rence constitutif est compos\u00e9 d\u2019une \u00e9quipe pluridisciplinaire sp\u00e9cialis\u00e9e dans la prise en charge des maladies pulmonaires rares. <\/strong><\/p><p>Ses missions :<\/p><ul><li>Assurer le diagnostic et la coordination des soins de la prise en charge des maladies pulmonaires rares de la r\u00e9gion Centre Val de Loire en collaboration avec le CHU d\u2019Orl\u00e9ans et l\u2019ensemble des CHG et des cabinets lib\u00e9raux de pneumologie<\/li><li>Coordonner et participer \u00e0 des projets de recherche (fondamentales, cliniques, \u00e9pid\u00e9miologiques) en collaboration avec le Centre d\u2019\u00e9tude des pathologies Respiratoires (unit\u00e9 Inserm U1100) <\/li><li>Promouvoir l\u2019enseignement et la formation aupr\u00e8s des \u00e9tudiants en m\u00e9decine, pharmacie, et autres composantes de la sant\u00e9<\/li><\/ul><p>Le centre est membre :<\/p><ul><li>De la Fili\u00e8re de Sant\u00e9 Maladies Rares <strong>RESPIFIL.<\/strong><\/li><\/ul>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-12c5587a elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"12c5587a\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-40f139f3\" data-id=\"40f139f3\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-40df4ad6 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"40df4ad6\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-2f83d9f9\" data-id=\"2f83d9f9\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2702fe4b elementor-widget elementor-widget-image\" data-id=\"2702fe4b\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"40\" height=\"40\" src=\"https:\/\/www.chu-tours.fr\/pemr-cvl\/wp-content\/uploads\/sites\/15\/2023\/02\/uk-flag-square-icon-128-40x40-1-40x40.png\" class=\"attachment-pictogramme-home size-pictogramme-home wp-image-372\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-4806b797\" data-id=\"4806b797\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-3ff17a9e elementor-widget elementor-widget-toggle\" data-id=\"3ff17a9e\" data-element_type=\"widget\" data-widget_type=\"toggle.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.23.0 - 15-07-2024 *\/\n.elementor-toggle{text-align:start}.elementor-toggle .elementor-tab-title{font-weight:700;line-height:1;margin:0;padding:15px;border-bottom:1px solid #d5d8dc;cursor:pointer;outline:none}.elementor-toggle .elementor-tab-title .elementor-toggle-icon{display:inline-block;width:1em}.elementor-toggle .elementor-tab-title .elementor-toggle-icon svg{margin-inline-start:-5px;width:1em;height:1em}.elementor-toggle .elementor-tab-title .elementor-toggle-icon.elementor-toggle-icon-right{float:right;text-align:right}.elementor-toggle .elementor-tab-title .elementor-toggle-icon.elementor-toggle-icon-left{float:left;text-align:left}.elementor-toggle .elementor-tab-title .elementor-toggle-icon .elementor-toggle-icon-closed{display:block}.elementor-toggle .elementor-tab-title .elementor-toggle-icon .elementor-toggle-icon-opened{display:none}.elementor-toggle .elementor-tab-title.elementor-active{border-bottom:none}.elementor-toggle .elementor-tab-title.elementor-active .elementor-toggle-icon-closed{display:none}.elementor-toggle .elementor-tab-title.elementor-active .elementor-toggle-icon-opened{display:block}.elementor-toggle .elementor-tab-content{padding:15px;border-bottom:1px solid #d5d8dc;display:none}@media (max-width:767px){.elementor-toggle .elementor-tab-title{padding:12px}.elementor-toggle .elementor-tab-content{padding:12px 10px}}.e-con-inner>.elementor-widget-toggle,.e-con>.elementor-widget-toggle{width:var(--container-widget-width);--flex-grow:var(--container-widget-flex-grow)}<\/style>\t\t<div class=\"elementor-toggle\">\n\t\t\t\t\t\t\t<div class=\"elementor-toggle-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-1071\" class=\"elementor-tab-title\" data-tab=\"1\" role=\"button\" aria-controls=\"elementor-tab-content-1071\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon elementor-toggle-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-closed\"><i class=\"fas fa-caret-right\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-opened\"><i class=\"elementor-toggle-icon-opened fas fa-caret-up\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-toggle-title\" tabindex=\"0\"><em>The reference centre is... <\/em><\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<div id=\"elementor-tab-content-1071\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"1\" role=\"region\" aria-labelledby=\"elementor-tab-title-1071\"><p>The reference centre is composed of a multidisciplinary team specialised in the care of in the management of rare pulmonary diseases.<\/p><p>The duties of the centre are:<\/p><ul><li>Ensure the diagnostic and the coordination of care in the Center Val de Loire region in collaboration with the Orl\u00e9ans University Hospital and all General Hospital Centers and private pulmonology practices<\/li><li>Organise and participate in research projects (fundamental, clinical, epidemiological) in collaboration with the Center for the Study of Respiratory Pathologies (Inserm unit U1100)<\/li><li>Promote education and training among students in medicine, pharmacy, and other health components<\/li><\/ul><p>The centre is a member :<\/p><ul><li>Of the French National Rare Disease Network <strong>(RESPIFIL)<\/strong><\/li><\/ul><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-1c076f45 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"1c076f45\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-75acbaf6\" data-id=\"75acbaf6\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4d4dfd43 elementor-widget elementor-widget-image\" data-id=\"4d4dfd43\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t<figure class=\"wp-caption\">\n\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"117\" src=\"https:\/\/www.chu-tours.fr\/pemr-cvl\/wp-content\/uploads\/sites\/15\/2024\/02\/logo_CRMPR-300x117.jpg\" class=\"attachment-medium size-medium wp-image-1916\" alt=\"Centre de R\u00e9f\u00e9rence Constitutif Maladies Pulmonaires Rares R\u00e9gion Centre-Val de Loire\" srcset=\"https:\/\/www.chu-tours.fr\/pemr-cvl\/wp-content\/uploads\/sites\/15\/2024\/02\/logo_CRMPR-300x117.jpg 300w, https:\/\/www.chu-tours.fr\/pemr-cvl\/wp-content\/uploads\/sites\/15\/2024\/02\/logo_CRMPR-768x301.jpg 768w, https:\/\/www.chu-tours.fr\/pemr-cvl\/wp-content\/uploads\/sites\/15\/2024\/02\/logo_CRMPR.jpg 820w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/>\t\t\t\t\t\t\t\t\t\t\t<figcaption class=\"widget-image-caption wp-caption-text\"><\/figcaption>\n\t\t\t\t\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-087abde elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"087abde\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-22ab965\" data-id=\"22ab965\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-186dccbd elementor-widget elementor-widget-toggle\" data-id=\"186dccbd\" data-element_type=\"widget\" data-widget_type=\"toggle.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-toggle\">\n\t\t\t\t\t\t\t<div class=\"elementor-toggle-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-4091\" class=\"elementor-tab-title\" data-tab=\"1\" role=\"button\" aria-controls=\"elementor-tab-content-4091\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon elementor-toggle-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-closed\"><i class=\"fas fa-caret-right\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-opened\"><i class=\"elementor-toggle-icon-opened fas fa-caret-up\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-toggle-title\" tabindex=\"0\"><span style=\"text-transform: uppercase\"><strong>Pathologies concern\u00e9es<\/strong><\/span><\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<div id=\"elementor-tab-content-4091\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"1\" role=\"region\" aria-labelledby=\"elementor-tab-title-4091\"><p><b>Liste non exhaustive des diff\u00e9rentes maladies prises en charge par le Centre de <\/b><b>R\u00e9f\u00e9rence Constitutif <\/b><\/p><ul><li><b>Pneumopathies interstitielles diffuses idiopathiques<\/b><\/li><li><b>Pneumopathies interstitielles diffuses idiopathiques principales<\/b><ul><li><a href=\"http:\/\/www.maladies-pulmonaires-rares.fr\/espace-patient\/FPI\">Fibrose pulmonaire idiopathique<\/a><\/li><li><a href=\"http:\/\/www.maladies-pulmonaires-rares.fr\/espace-patient\/PINS\">Pneumopathie interstitielle non sp\u00e9cifique<\/a><\/li><li><a href=\"http:\/\/www.maladies-pulmonaires-rares.fr\/espace-patient\/RB-ILD\">Bronchiolite respiratoire avec pneumopathie interstitielle diffuse<\/a><\/li><li><a href=\"http:\/\/www.maladies-pulmonaires-rares.fr\/espace-patient\/PID\">Pneumopathie interstitielle desquamative<\/a><\/li><li><a href=\"http:\/\/www.maladies-pulmonaires-rares.fr\/espace-patient\/POC\">Pneumopathie organis\u00e9e cryptog\u00e9nique<\/a><\/li><li><a href=\"http:\/\/www.maladies-pulmonaires-rares.fr\/espace-patient\/PIA\">Pneumopathie interstitielle aigu\u00eb <\/a><\/li><\/ul><\/li><li><b>Pneumopathies interstitielles diffuses idiopathiques plus rares<\/b><ul><li><a href=\"http:\/\/www.maladies-pulmonaires-rares.fr\/espace-patient\/PIL\">Pneumopathie interstitielle lympho\u00efde idiopathique<\/a><\/li><\/ul><\/li><\/ul><ul><li><b>Pneumopathies interstitielles diffuses idiopathiques inclassables<\/b><\/li><li><b>Maladies pulmonaires <\/b><b>hyper\u00e9osinophiliques<\/b><\/li><li><a href=\"http:\/\/www.maladies-pulmonaires-rares.fr\/espace-patient\/PCIE\">Pneumopathie chronique idiopathique \u00e0 \u00e9osinophiles<\/a><\/li><li><a href=\"http:\/\/www.maladies-pulmonaires-rares.fr\/espace-patient\/PAIE\">Pneumopathie aig\u00fce idiopathique \u00e0 \u00e9osinophiles<\/a><\/li><li><b><a href=\"http:\/\/www.maladies-pulmonaires-rares.fr\/espace-patient\/SEF\">Syndrome d&#8217;emphys\u00e8me et fibrose pulmonaires combin\u00e9s<\/a><\/b><\/li><li><b>Lymphangiol\u00e9iomyomatose<\/b><\/li><li><a href=\"http:\/\/www.maladies-pulmonaires-rares.fr\/espace-patient\/LAM\">Lymphangiol\u00e9iomyomatose<\/a><a href=\"http:\/\/www.maladies-pulmonaires-rares.fr\/espace-patient\/LAM\"> sporadique<\/a><\/li><li><a href=\"http:\/\/www.maladies-pulmonaires-rares.fr\/espace-patient\/STB\">Lymphangiol\u00e9iomyomatose<\/a><a href=\"http:\/\/www.maladies-pulmonaires-rares.fr\/espace-patient\/STB\"> associ\u00e9e \u00e0 la scl\u00e9rose tub\u00e9reuse de Bourneville <\/a><\/li><li><b>Autres maladies kystiques multiples pulmonaires (MKMP)<\/b><\/li><li><b>Dyskin\u00e9sie ciliaire primitive pulmonaire<\/b><\/li><li><b>Pneumopathie organis\u00e9e<\/b><\/li><li><b>Vascularites pulmonaires<\/b><\/li><li><a href=\"http:\/\/www.maladies-pulmonaires-rares.fr\/espace-patient\/GEPA\">Granulomatose \u00e9osinophilique avec <\/a><a href=\"http:\/\/www.maladies-pulmonaires-rares.fr\/espace-patient\/GEPA\">polyang\u00e9ite<\/a><a href=\"http:\/\/www.maladies-pulmonaires-rares.fr\/espace-patient\/GEPA\"> (ex. syndrome de <\/a><a href=\"http:\/\/www.maladies-pulmonaires-rares.fr\/espace-patient\/GEPA\">Churg<\/a><a href=\"http:\/\/www.maladies-pulmonaires-rares.fr\/espace-patient\/GEPA\"> et Strauss)<\/a><\/li><li><b>Bronchiolites et BPCO non tabagiques<\/b><\/li><li><b>Syndromes h\u00e9morragiques alv\u00e9olaires<\/b><\/li><li><a href=\"http:\/\/www.maladies-pulmonaires-rares.fr\/espace-patient\/Goodpasture\">Maladie des anticorps anti-membrane basale glom\u00e9rulaire (syndrome de <\/a><a href=\"http:\/\/www.maladies-pulmonaires-rares.fr\/espace-patient\/Goodpasture\">Goodpasture<\/a><a href=\"http:\/\/www.maladies-pulmonaires-rares.fr\/espace-patient\/Goodpasture\">)<\/a><\/li><li><b>Hypertension pulmonaire \u00ab\u00a0disproportionn\u00e9e\u00a0\u00bb des maladies rares pulmonaires <\/b><\/li><li><b>Trach\u00e9opathies<\/b><\/li><li><b>Prot\u00e9inose<\/b><b> alv\u00e9olaire<\/b><\/li><li><b><a href=\"http:\/\/www.maladies-pulmonaires-rares.fr\/espace-patient\/MRO\">T\u00e9langiectasie h\u00e9morragique h\u00e9r\u00e9ditaire avec malformations art\u00e9rioveineuses pulmonaires (Maladie de Rendu-Osler)<\/a><\/b><\/li><li><b>Amylose et d\u00e9p\u00f4ts <\/b><b>immunoglobuliniques<\/b><b> non-amylo\u00efdes bronchopulmonaires<\/b><\/li><li><b>Pneumopathies interstitielles diffuses rares autres que celles cit\u00e9es ci-dessus<\/b><\/li><li><b>Emphys\u00e8me par d\u00e9ficit en alpha-1-antitrypsine<\/b><\/li><li><b>Divers<\/b><\/li><\/ul><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-94efc57\" data-id=\"94efc57\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-c96e02c elementor-widget elementor-widget-image\" data-id=\"c96e02c\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"419\" height=\"595\" src=\"https:\/\/www.chu-tours.fr\/pemr-cvl\/wp-content\/uploads\/sites\/15\/2024\/02\/reseau-Respifil.png\" class=\"attachment-large size-large wp-image-1918\" alt=\"RESPIFIL\" srcset=\"https:\/\/www.chu-tours.fr\/pemr-cvl\/wp-content\/uploads\/sites\/15\/2024\/02\/reseau-Respifil.png 419w, https:\/\/www.chu-tours.fr\/pemr-cvl\/wp-content\/uploads\/sites\/15\/2024\/02\/reseau-Respifil-211x300.png 211w\" sizes=\"(max-width: 419px) 100vw, 419px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-dada410 elementor-widget elementor-widget-text-editor\" data-id=\"dada410\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h3>COMBIEN DE PERSONNES SONT ATTEINTES DE CETTE MALADIE ?<\/h3><p>La pr\u00e9valence de chacune des maladies pulmonaires rares est &lt; 30\/100000 habitants<\/p><h3>A QUOI EST-ELLE DUE ?<\/h3><p>Elles ont des origines multiples et variables : origine g\u00e9n\u00e9tique ou cong\u00e9nitale, li\u00e9e \u00e0 la pollution ext\u00e9rieure ou int\u00e9rieure, au tabac ou au cannabis. La cause reste parfois inconnue (ou idiopathique).<\/p><h3>QUELLE EST L\u2019IMPACT POUR LE PATIENT ET SA FAMILLE ?<\/h3><p>Elles peuvent entrainer des l\u00e9sions irr\u00e9versibles du poumon et favoriser l\u2019apparition d\u2019une insuffisance respiratoire chronique n\u00e9cessitant de l\u2019oxyg\u00e8ne, un appareil ventilatoire voire dans certains cas une transplantation pulmonaire<\/p><p>Plus d\u2019informations sur les maladies rares : <a href=\"http:\/\/www.orphanet.fr\" target=\"_blank\" rel=\"noopener\">www.orphanet.fr<\/a><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<div class=\"elementor-element elementor-element-56c78c4b elementor-widget elementor-widget-image\" data-id=\"56c78c4b\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t<figure class=\"wp-caption\">\n\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"300\" src=\"https:\/\/www.chu-tours.fr\/pemr-cvl\/wp-content\/uploads\/sites\/15\/2023\/02\/equipe-300x300-1-300x300.png\" class=\"attachment-medium size-medium wp-image-366\" alt=\"\" srcset=\"https:\/\/www.chu-tours.fr\/pemr-cvl\/wp-content\/uploads\/sites\/15\/2023\/02\/equipe-300x300-1.png 300w, https:\/\/www.chu-tours.fr\/pemr-cvl\/wp-content\/uploads\/sites\/15\/2023\/02\/equipe-300x300-1-150x150.png 150w, https:\/\/www.chu-tours.fr\/pemr-cvl\/wp-content\/uploads\/sites\/15\/2023\/02\/equipe-300x300-1-40x40.png 40w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/>\t\t\t\t\t\t\t\t\t\t\t<figcaption class=\"widget-image-caption wp-caption-text\">L'\u00c9QUIPE<\/figcaption>\n\t\t\t\t\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-14ea675 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"14ea675\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-679a2560\" data-id=\"679a2560\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-14ea4e7c elementor-widget elementor-widget-toggle\" data-id=\"14ea4e7c\" data-element_type=\"widget\" data-widget_type=\"toggle.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-toggle\">\n\t\t\t\t\t\t\t<div class=\"elementor-toggle-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-3501\" class=\"elementor-tab-title\" data-tab=\"1\" role=\"button\" aria-controls=\"elementor-tab-content-3501\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon elementor-toggle-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-closed\"><i class=\"fas fa-caret-right\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-opened\"><i class=\"elementor-toggle-icon-opened fas fa-caret-up\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-toggle-title\" tabindex=\"0\"><span style=\"text-transform: uppercase\"><strong>L'\u00e9quipe m\u00e9dicale<\/strong><\/span><\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<div id=\"elementor-tab-content-3501\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"1\" role=\"region\" aria-labelledby=\"elementor-tab-title-3501\"><h3><b>\u00c9quipe m\u00e9dicale :<\/b><\/h3><p><b>M\u00e9decin coordonnateur :<\/b><\/p><ul><li>Pr Sylvain Marchand-Adam<\/li><\/ul><p><b>L\u2019\u00e9quipe <\/b><b>r\u00e9f\u00e9rente Pneumologie<\/b><\/p><ul><li>T\u00e9l : 02 47 47 37 87 <\/li><li>Pr Sylvain Marchand-Adam <\/li><li>Pr Laurent Plantier<\/li><li>Dr Thomas Flament<\/li><li>Dr Sylvie Legu\u00e9<\/li><li>Dr Pascal Magro<\/li><li>Dr Julie Mankikian<\/li><\/ul><p><b>M\u00e9decine <\/b><b>interne<br \/><\/b><\/p><ul><li>Dr Benjamin Thoreau 02 47 47 47 47<\/li><\/ul><p><b>P\u00e9diatrie<br \/><\/b><\/p><ul><li>Dr Isabelle Gibertini 02 47 47 47 55<\/li><\/ul><p><b>Conseill\u00e8re <\/b><b>en g\u00e9n\u00e9tique <\/b><\/p><ul><li>Mme Soizic Lebrun 02 18 37 06 13<\/li><\/ul><h3><b>Services collaborant avec le CRMR<\/b><\/h3><p><b>CH Simone Veil de Blois <\/b><\/p><ul><li>Service de Pneumologie<\/li><li>Dr Timoth\u00e9e Blin 02 54 55 63 15<\/li><\/ul><p><b>Espace Sant\u00e9 Blois <\/b><\/p><ul><li>Service de Pneumologie<\/li><li>Dr Marc Nasser 02 54 56 83 83<\/li><\/ul><p><b>CHU Orl\u00e9ans <\/b><\/p><ul><li>Service de Pneumologie<\/li><li>Dr Marion Campana 02 38 61 31 91<\/li><\/ul><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-4b855974\" data-id=\"4b855974\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-11cdf9d0 elementor-widget elementor-widget-toggle\" data-id=\"11cdf9d0\" data-element_type=\"widget\" data-widget_type=\"toggle.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-toggle\">\n\t\t\t\t\t\t\t<div class=\"elementor-toggle-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-2981\" class=\"elementor-tab-title\" data-tab=\"1\" role=\"button\" aria-controls=\"elementor-tab-content-2981\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon elementor-toggle-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-closed\"><i class=\"fas fa-caret-right\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-opened\"><i class=\"elementor-toggle-icon-opened fas fa-caret-up\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-toggle-title\" tabindex=\"0\"><span style=\"text-transform: uppercase\"><strong>l'\u00e9quipe param\u00e9dicale<\/strong><\/span><\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<div id=\"elementor-tab-content-2981\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"1\" role=\"region\" aria-labelledby=\"elementor-tab-title-2981\"><h3><b>\u00c9quipe <\/b><b>param\u00e9dicale :<\/b><\/h3><p><b>Infirmi\u00e8re r\u00e9f\u00e9rente<\/b><\/p><ul><li>Mme Manon Dalmasso 02 47 47 37 87<\/li><\/ul><p><b>Kin\u00e9sith\u00e9rapeutes <\/b><b>r\u00e9f\u00e9rent.e.s<\/b><b><br \/><\/b><\/p><ul><li>Mme Melissa Creiche 02 47 47 47 47<\/li><li>M. Guillaume Buckel 02 47 47 47 47<\/li><\/ul><p><b>Psychologue<\/b><b><br \/><\/b><\/p><ul><li>Mme Nathalie Noury 02 47 47 47 47<\/li><\/ul><p><b>Assistante sociale<br \/><\/b><\/p><ul><li>Mme Alicia Malonga 02 34 37 89 72<\/li><\/ul><h3><b>Laboratoires <\/b><b>de diagnostic<\/b><\/h3><p><b>Anatomopathologie<br \/><\/b><\/p><ul><li>Dr Damien Sizaret 02 47 47 81 12<\/li><\/ul><p><b>Pharmacologie m\u00e9dicale<br \/><\/b><\/p><ul><li>Dr Th\u00e9odora Bejan-Angoulvant 02 47 47 71 29<\/li><\/ul><p><b>Service <\/b><b>de Radiologie\u00a0 <\/b>02 47 47 88 33<\/p><h3><b>Pour prendre rendez-vous : <\/b><\/h3><p><b>H\u00f4pital Bretonneau B\u00e2timent <\/b><b>B1A <\/b><b>\u00a0 \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/b><\/p><p>Coordonn\u00e9es du secr\u00e9tariat :<\/p><ul><li><b>T\u00e9l : 02 47 47 37 87<\/b><\/li><\/ul><p><strong>Mail<\/strong> : <a href=\"mailto:pneumologie@chu-tours.fr\" target=\"_blank\" rel=\"noopener\">pneumologie@chu-tours.fr<\/a><\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-7badb737 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"7badb737\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-e453e17\" data-id=\"e453e17\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7891a304 elementor-widget elementor-widget-image\" data-id=\"7891a304\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t<figure class=\"wp-caption\">\n\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"240\" src=\"https:\/\/www.chu-tours.fr\/pemr-cvl\/wp-content\/uploads\/sites\/15\/2023\/02\/recherche-300x240-2.png\" class=\"attachment-medium size-medium wp-image-371\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t<figcaption class=\"widget-image-caption wp-caption-text\">PROTOCOLES EN COURS<\/figcaption>\n\t\t\t\t\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5cbc84cb elementor-widget elementor-widget-toggle\" data-id=\"5cbc84cb\" data-element_type=\"widget\" data-widget_type=\"toggle.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-toggle\">\n\t\t\t\t\t\t\t<div class=\"elementor-toggle-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-1551\" class=\"elementor-tab-title\" data-tab=\"1\" role=\"button\" aria-controls=\"elementor-tab-content-1551\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon elementor-toggle-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-closed\"><i class=\"fas fa-caret-right\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-opened\"><i class=\"elementor-toggle-icon-opened fas fa-caret-up\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-toggle-title\" tabindex=\"0\"><span style=\"text-transform: uppercase\"><strong>Protocoles en cours<\/strong><\/span><\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<div id=\"elementor-tab-content-1551\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"1\" role=\"region\" aria-labelledby=\"elementor-tab-title-1551\"><p><b>De nombreux protocoles de recherches cliniques et de recherches fondamentales sont en cours<\/b><\/p><ol><li>La th\u00e9matique principale tourne autour des anticorps th\u00e9rapeutiques dans le cadre du LABEX MabImprove.<\/li><li>PHRC nationaux sur le b\u00e9n\u00e9fice du rituximab dans les pneumopathies interstitielles diffuses. L&#8217;un des 2 est fini sur les pneumopathies interstitielles non sp\u00e9cifiques avec soumission \u00e0 European Respiratory Journal. L&#8217;autre a d\u00e9but\u00e9 en octobre 2022 et porte sur les pneumopathies d&#8217;hypersensibilit\u00e9s. Deux autres projets d\u00e9buteront en 2024 avec la collaboration FAI2R sur la scl\u00e9rodermie et la polyarthrite rhumato\u00efde.<\/li><li>D&#8217;autres \u00e9tudes de recherche clinique portent sur l&#8217;int\u00e9r\u00eat de l&#8217;\u00e9chographie thoracique dans le suivi des PID :<ul><li><b>l&#8217;\u00e9tude <\/b><b>Toupie <\/b>portant sur le suivi longitudinal de patients atteints de fibrose pulmonaire idiopathique est finie avec l&#8217;analyse des donn\u00e9es en cours.<\/li><li><b>L&#8217;\u00e9tude <\/b><b>PRECOSS <\/b>est termin\u00e9e et s&#8217;int\u00e9resse \u00e0 l&#8217;analyse des caract\u00e9ristiques des patients atteints de scl\u00e9rodermie avec des anomalies \u00e9chographiques thoraciques mais \u00e0 scanner thoracique normal. Article en cours de soumission.<\/li><li><b>Projet <\/b><b>TURTLE <\/b>&#8220;Thoracic Ultrasound for acute dyspnea in interstitial Lung Disease&#8221; : termin\u00e9 est portant sur la s\u00e9miologie \u00e9chographique lors d&#8217;une dyspn\u00e9e aigu\u00eb chez les patients atteints de pneumopathie interstitielle diffuse. Les r\u00e9sultats sont en cours d\u2019analyse.<\/li><li><b>Projet EARLIER<\/b>, sur le depistage des PID par \u00e9chographie thoracique au cours de la polyarthrite rhumato\u00efde. D\u00e9butera courant 2024.<\/li><li><b>Projet TOUCANS<\/b>, sur l&#8217;int\u00e9r\u00eat des biopsies pulmonaires \u00e9choguid\u00e9es au cours des PID<\/li><li>Une collaboration avec polytech Tours a pour but d&#8217;\u00e9tudier l&#8217;int\u00e9r\u00eat d&#8217;une analyse des boucles d&#8217;\u00e9chographie par intelligence artificielle.<\/li><\/ul><\/li><li>Des \u00e9tudes sur l&#8217;int\u00e9r\u00eat des nouvelles techniques des explorations fonctionnelles respiratoires sont en cours : <b>l&#8217;\u00e9tude Oscillo<\/b>, \u00e9tudie l&#8217;int\u00e9r\u00eat de l&#8217;oscillom\u00e9trie chez les patients atteints de fibrose pulmonaire idiopathique (\u00e9tude soumise); Dans l&#8217;\u00e9tude PRECOSS (ci dessus), un volet porte sur l&#8217;EFX.<\/li><li>Des \u00e9tudes transversales en collaboration avec l&#8217;\u00e9quipe 2 du CEPR INSERM UMR 1100 sont en cours telle que l&#8217;\u00e9tude LAM-CAK (fin des inclusion en septembre 22) qui est une \u00e9tude exploratrice de l&#8217;expression et de l&#8217;activit\u00e9 de la cathepsine K dans la lymphangioleiomyomatose et la sclerose tubereuse de Bourneville (\u00e9tude financ\u00e9e par l&#8217;association de patients FLAM). Un projet est en r\u00e9flexion sur les inhibiteurs de HDAC et sur\u00a0 la cathespine V (intervenant dans la prot\u00e9olyse de l&#8217;\u00e9lastine) dans les fibrose pulmonaires progressives et en particulier dans la fibro\u00e9lastose pleuropulmonaire. Une \u00e9tude sur l&#8217;int\u00e9r\u00eat des inhibiteurs de la cathepsine C (activateur de la PR3) dans la granulomatose avec polyang\u00e9\u00efte (avec pr\u00e9sence d&#8217;autoanticorps anti PR3) est r\u00e9alis\u00e9e en cours de r\u00e9alisation<\/li><\/ol><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-6048b8cb elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"6048b8cb\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-5f33417d\" data-id=\"5f33417d\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-24115f23 elementor-widget elementor-widget-image\" data-id=\"24115f23\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t<figure class=\"wp-caption\">\n\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"263\" src=\"https:\/\/www.chu-tours.fr\/pemr-cvl\/wp-content\/uploads\/sites\/15\/2023\/02\/enseignement-300x263-1.png\" class=\"attachment-medium size-medium wp-image-365\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t<figcaption class=\"widget-image-caption wp-caption-text\">ENSEIGNEMENT<\/figcaption>\n\t\t\t\t\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4b94aaf3 elementor-widget elementor-widget-toggle\" data-id=\"4b94aaf3\" data-element_type=\"widget\" data-widget_type=\"toggle.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-toggle\">\n\t\t\t\t\t\t\t<div class=\"elementor-toggle-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-1261\" class=\"elementor-tab-title\" data-tab=\"1\" role=\"button\" aria-controls=\"elementor-tab-content-1261\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon elementor-toggle-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-closed\"><i class=\"fas fa-caret-right\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-opened\"><i class=\"elementor-toggle-icon-opened fas fa-caret-up\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-toggle-title\" tabindex=\"0\"><span style=\"text-transform: uppercase\"><strong>Enseignement<\/strong><\/span><\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<div id=\"elementor-tab-content-1261\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"1\" role=\"region\" aria-labelledby=\"elementor-tab-title-1261\"><h3>Formation Internes du 3\u00e8me cycle :<\/h3><ul><li><b>Formation de niveau \u00e0 l\u2019\u00e9chographie thoracique<\/b><\/li><\/ul><h3>Les Formations Post-Universitaires :<\/h3><ul><li><b>DIU d\u2019\u00e9chographie thoracique<\/b><\/li><\/ul><p>\u00a0<\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-199eb617 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"199eb617\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-469bbef6\" data-id=\"469bbef6\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-68c7c8c8 elementor-widget elementor-widget-image\" data-id=\"68c7c8c8\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t<figure class=\"wp-caption\">\n\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"212\" src=\"https:\/\/www.chu-tours.fr\/pemr-cvl\/wp-content\/uploads\/sites\/15\/2023\/02\/outils-300x212-1.png\" class=\"attachment-medium size-medium wp-image-367\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t<figcaption class=\"widget-image-caption wp-caption-text\">OUTILS<\/figcaption>\n\t\t\t\t\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7d3a8f7e elementor-widget elementor-widget-toggle\" data-id=\"7d3a8f7e\" data-element_type=\"widget\" data-widget_type=\"toggle.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-toggle\">\n\t\t\t\t\t\t\t<div class=\"elementor-toggle-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-2101\" class=\"elementor-tab-title\" data-tab=\"1\" role=\"button\" aria-controls=\"elementor-tab-content-2101\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon elementor-toggle-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-closed\"><i class=\"fas fa-caret-right\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-opened\"><i class=\"elementor-toggle-icon-opened fas fa-caret-up\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-toggle-title\" tabindex=\"0\"><span style=\"text-transform: uppercase\"><strong>Outils<\/strong><\/span><\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<div id=\"elementor-tab-content-2101\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"1\" role=\"region\" aria-labelledby=\"elementor-tab-title-2101\"><h3><b>Protocoles Nationaux de Diagnostic et de Soins (PNDS<\/b><b>)<\/b><\/h3><p><b>D\u00e9finition HAS :<\/b><\/p><p><i>L\u2019<\/i><b><i>objectif d\u2019un PNDS<\/i><\/b><i> est d\u2019expliciter aux professionnels concern\u00e9s la prise en charge diagnostique et th\u00e9rapeutique optimale actuelle et le parcours de soins d\u2019un patient atteint d\u2019une maladie rare donn\u00e9e. Il a pour but d\u2019optimiser et d\u2019harmoniser la prise en charge et le suivi de la maladie rare sur l\u2019ensemble du territoire.<\/i><\/p><p><i>Le PNDS peut servir de r\u00e9f\u00e9rence au m\u00e9decin traitant (m\u00e9decin d\u00e9sign\u00e9 par le patient aupr\u00e8s de la Caisse d\u2019Assurance Maladie) en concertation avec le m\u00e9decin sp\u00e9cialiste notamment au moment d\u2019\u00e9tablir le protocole de soins conjointement avec le m\u00e9decin conseil et le patient, dans le cas d&#8217;une demande d&#8217;exon\u00e9ration du ticket mod\u00e9rateur au titre d&#8217;une affection hors liste<\/i><i>.<\/i><\/p><h3><b>PNDS\/Recommandations <\/b><b>de Bonnes <\/b><b>Pratiques\/<\/b><b>Carte <\/b><b>d&#8217;urgence<\/b><\/h3><p>Merci de se reporter sur cette page internet :<\/p><ul><li><i><a href=\"http:\/\/www.maladies-pulmonaires-rares.fr\/espace-patient\/services-aide-patients\" target=\"_blank\" rel=\"noopener\">http:\/\/www.maladies-pulmonaires-rares.fr\/espace-patient\/services-aide-patients<\/a><\/i><i><\/i><i><\/i><\/li><\/ul><h3><b>Programmes <\/b><b>d\u2019Education Th\u00e9rapeutique du Patient (ETP<\/b><b>)<\/b><\/h3><p>Dans le cadre d\u2019un partenariat avec l\u2019association Espace du Souffle des programmes d\u2019ETP sont d\u00e9j\u00e0 r\u00e9alis\u00e9s pour :<\/p><ul><li>Les patients atteints de dilatations des bronches<\/li><li>Les patients atteints de maladies pulmonaires rares au stade d\u2019insuffisance respiratoire chronique<\/li><\/ul><p>Un programme sp\u00e9cifique pour les patients atteints de pneumopathie interstitielle diffuse est en cours d\u2019\u00e9laboration.<\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-6d72e75e elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"6d72e75e\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-177bdbdc\" data-id=\"177bdbdc\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-6a5c4c44 elementor-widget elementor-widget-image\" data-id=\"6a5c4c44\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t<figure class=\"wp-caption\">\n\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"192\" src=\"https:\/\/www.chu-tours.fr\/pemr-cvl\/wp-content\/uploads\/sites\/15\/2023\/02\/liens-300x192-1.png\" class=\"attachment-medium size-medium wp-image-370\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t<figcaption class=\"widget-image-caption wp-caption-text\">LIENS<\/figcaption>\n\t\t\t\t\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-160a6f7f elementor-widget elementor-widget-toggle\" data-id=\"160a6f7f\" data-element_type=\"widget\" data-widget_type=\"toggle.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-toggle\">\n\t\t\t\t\t\t\t<div class=\"elementor-toggle-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-3691\" class=\"elementor-tab-title\" data-tab=\"1\" role=\"button\" aria-controls=\"elementor-tab-content-3691\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon elementor-toggle-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-closed\"><i class=\"fas fa-caret-right\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-opened\"><i class=\"elementor-toggle-icon-opened fas fa-caret-up\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-toggle-title\" tabindex=\"0\"><span style=\"text-transform: uppercase\"><strong>Liens<\/strong><\/span><\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<div id=\"elementor-tab-content-3691\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"1\" role=\"region\" aria-labelledby=\"elementor-tab-title-3691\"><h3><b>Fili\u00e8re de sant\u00e9 <\/b><b>:<br \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-1917\" src=\"https:\/\/www.chu-tours.fr\/pemr-cvl\/wp-content\/uploads\/sites\/15\/2024\/02\/logo_Respifil.png\" alt=\"RESPIFIL\" width=\"207\" height=\"83\" \/><br \/><\/b><\/h3><ul><li>La fili\u00e8re de sant\u00e9 des maladies respiratoires rares : <a href=\"http:\/\/www.respifil.fr\/\" target=\"_blank\" rel=\"noopener\">www.respifil.fr<\/a><\/li><\/ul><h3><b>Soci\u00e9t\u00e9s Savantes :<\/b><\/h3><ul><li>Soci\u00e9t\u00e9 de Pneumologie de Langue Fran\u00e7aise : <a href=\"http:\/\/www.splf.fr\/\" target=\"_blank\" rel=\"noopener\">www.splf.fr<\/a><\/li><li>F\u00e9d\u00e9ration Fran\u00e7aise de Pneumologie et Conseil National Professionnel de Pneumologie : <a href=\"http:\/\/www.ffpneumologie.org\/\" target=\"_blank\" rel=\"noopener\">www.ffpneumologie.org<\/a><\/li><\/ul><h3><b>Les Associations de patients :<\/b><\/h3><ul><li>Association Fibroses Pulmonaires France : <a href=\"https:\/\/asso-fpf.com\/\" target=\"_blank\" rel=\"noopener\">https:\/\/asso-fpf.com<\/a><a href=\"https:\/\/asso-fpf.com\/\">\/<\/a><\/li><li>Association FLAM ( France Lymphangiol\u00e9iomyomatose) : <a href=\"https:\/\/francelam.org\/\" target=\"_blank\" rel=\"noopener\">https:\/\/francelam.org<\/a><a href=\"https:\/\/francelam.org\/\">\/<\/a><\/li><\/ul><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Centre de R\u00e9f\u00e9rence Constitutif Maladies Pulmonaires RaresR\u00e9gion Centre-Val de Loire Le Centre de r\u00e9f\u00e9rence constitutif est compos\u00e9 d\u2019une \u00e9quipe pluridisciplinaire sp\u00e9cialis\u00e9e dans la prise en charge des maladies pulmonaires rares. Ses missions : Assurer le diagnostic et la coordination des soins de la prise en charge des maladies pulmonaires rares de la r\u00e9gion Centre Val [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_seopress_robots_primary_cat":"","_seopress_titles_title":"Centre de R\u00e9f\u00e9rence Constitutif Maladies Pulmonaires Rares  R\u00e9gion Centre-Val de Loire","_seopress_titles_desc":"Le Centre de r\u00e9f\u00e9rence constitutif est compos\u00e9 d\u2019une \u00e9quipe pluridisciplinaire sp\u00e9cialis\u00e9e dans la prise en charge des maladies pulmonaires rares. 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